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产地 | 中国 |
品牌 | 爱必信(absin) |
货号 | abs133021 |
保存条件 | 见爱必信官网 |
应用范围 | 见爱必信官网 |
抗体名 | RIPK1 |
是否单克隆 | 否 |
克隆性 | 见爱必信官网 |
靶点 | 见爱必信官网 |
适应物种 | 见爱必信官网 |
形态 | 见爱必信官网 |
宿主 | 见爱必信官网 |
包装规格 | 50ug,100ug |
纯度 | % |
亚型 | 见爱必信官网 |
标识物 | 见爱必信官网 |
浓度 | 见爱必信官网% |
免疫原 | 见爱必信官网 |
是否进口 | 否 |
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抗体描述: 产品名称:Rabbit anti-RIPK1 Polyclonal Antibody 产品别名:RIPK1抗体 宿主:Rabbit 反应种属:Human 克隆性:Polyclonal Antibody 保存方法:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles 产品描述:Essential adapter molecule for the activation of NF-kappa-B. Following different upstream signals (binding of inflammatory cytokines, stimulation of pathogen recognition receptors, or DNA damage), particular RIPK1-containing complexes are formed, initiating a limited number of cellular responses. Upon TNFA stimulation RIPK1 is recruited to a TRADD-TRAF complex initiated by TNFR1 trimerization. There, it is ubiquitinated via 'Lys-63'-link chains, inducing its association with the IKK complex, and its activation through NEMO binding of polyubiquitin chains. 用途范围: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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