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- 品牌：爱必信(absin)
- 产地：中国
- 货号：abs133010
- 价格： ￥1500/支
- 发布日期： 2022-04-08
- 更新日期： 2025-07-20
| 产地 | 中国 |
| 品牌 | 爱必信(absin) |
| 货号 | abs133010 |
| 保存条件 | 见爱必信官网 |
| 应用范围 | 见爱必信官网 |
| 抗体名 | ATR |
| 是否单克隆 | 否 |
| 克隆性 | 见爱必信官网 |
| 靶点 | 见爱必信官网 |
| 适应物种 | 见爱必信官网 |
| 形态 | 见爱必信官网 |
| 宿主 | 见爱必信官网 |
| 包装规格 | 50ug,100ug |
| 纯度 | % |
| 亚型 | 见爱必信官网 |
| 标识物 | 见爱必信官网 |
| 浓度 | 见爱必信官网% |
| 免疫原 | 见爱必信官网 |
| 是否进口 | 否 |
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公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)!
抗体描述: 产品名称:Rabbit anti-ATR Polyclonal Antibody 产品别名:ATR抗体 宿主:Rabbit 反应种属:Human 克隆性:Polyclonal Antibody 保存方法:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles 产品描述:Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates BRCA1, CHEK1, MCM2, RAD17, RPA2, SMC1 and p53/TP53, which collectively inhibit DNA replication and mitosis and promote DNA repair, recombination and apoptosis. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at sites of DNA damage, thereby regulating DNA damage response mechanism. Required for FANCD2 ubiquitination. Critical for maintenance of fragile site stability and efficient regulation of centrosome duplication. 用途范围: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
产品信息订购:
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- 手机：18438616290