公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)!

抗体描述:

产品名称:Rabbit anti-RhoA Polyclonal Antibody

产品别名:RhoA抗体  

宿主:Rabbit

反应种属:Human;Mouse;Rat

克隆性:Polyclonal Antibody

保存方法:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles

产品描述:Rho family small GTPases, including Rho, Rac and cdc42, act as molecular switches, regulating processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze the exchange of bound GDP for GTP, and inhibited by GTPase activating proteins (GAPs), which catalyze the hydrolysis of GTP to GDP. A third level of regulation is provided by the stoichiometric binding of Rho GDP dissociation inhibitor (RhoGDI) (1). RhoA, RhoB and RhoC are highly homologous, but appear to have divergent biological functions. Carboxy-terminal modifications and differences in subcellular localization allow these three proteins to respond to and act on distinct signaling molecules (2,3). Functions of RhoA, the most highly studied of these three, include regulation of actomyosin contractility (4), cytokinesis (5), focal adhesion assembly (6) and cell polarity (7).

用途范围: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

产品信息订购:

产品更多信息请进入爱必信网站咨询