T-cell surface glycoprotein CD3 delta chain; T-cell receptor T3 delta chain; CD3d

HEK 293

Detects a band of approximately 18-25 kDa(Predicted molecular weight:11.2 kDa)

Lyophilized Powder

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.

C-10His

＞90% by SDS-PAGE

<1EU/ug

Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

Within 1 week, 2 to 8 °C under sterile conditions after reconstitution. 12 months from date of receipt, -20 to -80 °C as supplied. Avoid repeated freeze-thaw cycles.

CD3 delta is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene.

P04234