Antalarmin (hydrochloride) is a non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist with a Ki of 1 nM. Antalarmin hydrochloride suppresses CRH-induced ACTH secretion and blocks CRH and novelty induced anxiety-like behavior in animal models. Antalarmin hydrochloride produces anti-inflammatory effects in arthritis models, and suppresses stress-induced gastric ulceration related to irritable bowel syndrome.

≥98%

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

安塔拉明盐酸盐

off-white solid

DMF : 20 mg/mL (48.19 mM; Need ultrasonic and warming)
Ethanol : 14 mg/mL (33.73 mM; Need ultrasonic and warming)
DMSO : 12.5 mg/mL (30.12 mM; Need ultrasonic and warming)