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20-羟基二十碳-5Z,8Z,11Z,14Z-四烯酸;20-HETE;79551-86-3
- 品牌：爱必信(absin)
- 产地：上海
- 型号：25ug;50ug
- 货号：abs42006088
- cas：79551-86-3
- 价格： ￥3032/支
- 发布日期： 2023-07-14
- 更新日期： 2025-03-28
产品详请
| 产地 | 上海 |
| 品牌 | 爱必信(absin) |
| 货号 | abs42006088 |
| 用途 | A cytochrome P450 (CYP450) metabolite that may play an autacoid role in cerebral and renal vasculature |
| 英文名称 | 20-HETE;20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid;20-hydroxy Arachidonic Acid |
| 包装规格 | 25ug;50ug |
| 纯度 | ≥98%% |
| CAS编号 | 79551-86-3 |
| 保质期 | Store at -20° C, 1 year |
| 是否进口 | 否 |
| 产品描述 | |
| 描述 |
20-HETE is a cytochrome P450 (CYP450) metabolite postulated to play an autacoid role in the cerebral and renal vasculature. In rat cerebral microvessels, this compound is a vasoconstrictor that mediates pressure-induced autoregulatory vasoconstriction. It is excreted mainly as the glucuronide conjugate where the concentration of free 20-HETE (20-40 pg/ml in human urine) is about 10-fold lower than the corresponding concentration of the 20-glucuronide. 20-HETE can be further metabolized by cyclooxygenase to 20-hydroxy PGG2 and 20-hydroxy PGH2.
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| 应用 |
A cytochrome P450 (CYP450) metabolite that may play an autacoid role in cerebral and renal vasculature
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| 纯度 |
≥98%
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| 浓度 |
100ug/ml
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| 储存/保存方法 |
Store at -20° C, 1 year
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| 形态 |
Liquid
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| 基本信息 | |
| 别名 |
20-羟基二十碳-5Z,8Z,11Z,14Z-四烯酸;20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid；20-hydroxy Arachidonic Acid
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| 外观 |
solution in ethanol
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| 沸点 |
78° C
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| 折射率 |
n20D 1.52 (Predicted)
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| PK值 |
pKa: 4.82 (Predicted), pKb: -2 (Predicted)
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| 可溶性/溶解性 |
Soluble in ethanol, DMSO, DMF, PBS (pH 7.2) (≥ 0.8 mg/ml), and 0.1 M Na2CO3 (2 mg/ml).
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| MDL |
MFCD00171542
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| PubChem CID |
5283157
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| Beilstein 注册 |
4693091
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