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20-羟基二十碳-5Z,8Z,11Z,14Z-四烯酸;20-HETE;79551-86-3
  • 品牌:爱必信(absin)
  • 产地:上海
  • 型号:25ug;50ug
  • 货号:abs42006088
  • cas:79551-86-3
  • 价格: ¥3032/支
  • 发布日期: 2023-07-14
  • 更新日期: 2024-05-14
产品详请
产地 上海
品牌 爱必信(absin)
货号 abs42006088
用途范围 A cytochrome P450 (CYP450) metabolite that may play an autacoid role in cerebral and renal vasculature
英文名称 20-HETE;20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid;20-hydroxy Arachidonic Acid
纯度 ≥98%%
CAS编号 79551-86-3
规格 25ug;50ug
保质期 Store at -20° C, 1 year
是否进口

    产品描述
描述
20-HETE is a cytochrome P450 (CYP450) metabolite postulated to play an autacoid role in the cerebral and renal vasculature. In rat cerebral microvessels, this compound is a vasoconstrictor that mediates pressure-induced autoregulatory vasoconstriction. It is excreted mainly as the glucuronide conjugate where the concentration of free 20-HETE (20-40 pg/ml in human urine) is about 10-fold lower than the corresponding concentration of the 20-glucuronide. 20-HETE can be further metabolized by cyclooxygenase to 20-hydroxy PGG2 and 20-hydroxy PGH2.
应用
A cytochrome P450 (CYP450) metabolite that may play an autacoid role in cerebral and renal vasculature
纯度
≥98%
浓度
100ug/ml
储存/保存方法
Store at -20° C, 1 year
形态
Liquid
    基本信息
别名
20-羟基二十碳-5Z,8Z,11Z,14Z-四烯酸;20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid;20-hydroxy Arachidonic Acid
外观
solution in ethanol
沸点
78° C
折射率
n20D 1.52 (Predicted)
PK值
pKa: 4.82 (Predicted), pKb: -2 (Predicted)
可溶性/溶解性
Soluble in ethanol, DMSO, DMF, PBS (pH 7.2) (≥ 0.8 mg/ml), and 0.1 M Na2CO3 (2 mg/ml).
MDL
MFCD00171542
PubChem CID
5283157
Beilstein 注册
4693091
分子结构图:


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