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产地 | 上海 |
品牌 | 爱必信(absin) |
货号 | abs42008915 |
用途 | A potent vasodilator that inhibits platelet aggregation and cysteine proteases |
包装规格 | 20mg;100mg |
CAS编号 | 16142-27-1 |
纯度 | ≥98%% |
是否进口 | 否 |
产品描述 | |
描述 |
3-Morpholinosydnonimine (SIN-1) is a metabolite of molsidomine which has been shown to decompose spontaneously in solution in the presence of oxygen. This reaction releases nitric oxide (NO) and superoxide anion, which under physiological conditions, react to produce peroxynitrite. SIN-1 is a potent vasodilator, activator of GCS (guanylyl cyclase), inhibitor of platelet aggregation, general cysteine protease inhibitor, and has been shown to produce significant protective effects in myocardial ischemia-reperfusion. Some of the effects of SIN-1 can be attenuated by nitroglycerin-induced tolerance. |
应用 |
A potent vasodilator that inhibits platelet aggregation and cysteine proteases
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纯度 |
≥98%
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储存/保存方法 |
Store at -20° C,2 years.
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基本信息 | |
别名 |
5-氨基-3-(4-吗啉基)-1,2,3-恶二唑盐酸盐;5-amino-3-(4-morpholinyl)-1,2,3-oxadiazolium chloride; (3-Morpholino-1,2,3-oxadiazol-3-ium-5-yl)amidehydrochloride;SIN-1 (chloride)
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外观 |
White solid
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可溶性/溶解性 |
Soluble in water (25 mg/ml), ethanol (10 mg/ml), and DMSO (10 mg/ml).
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