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N-乙酰基-S-法呢基-L-半胱氨酸;135304-07-3
  • 品牌:爱必信(absin)
  • 产地:上海
  • 货号:abs42022842
  • cas:135304-07-3
  • 价格: ¥1166/瓶
  • 发布日期: 2023-07-19
  • 更新日期: 2024-05-24
产品详请
产地 上海
品牌 爱必信(absin)
货号 abs42022842
用途 An inhibitor of S-farnesylcysteine methyl transferase
纯度 0.98%
CAS编号 135304-07-3
规格 5mg
是否进口

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试剂描述:

产品名称:N-乙酰基-S-法呢基-L-半胱氨酸

产品别名:

CAS号:135304-07-3

英文别名:N-乙酰基-S-法呢基-L-半胱氨酸

分子量:367.55

分子式:C20H33NO3S

纯度:≥98%

外观:见爱必信官网

保存方法:Store at -20° C

描述:N-Acetyl-S-farnesyl-L-cysteine is a synthetically derivatized cysteine amino acid inhibitor of S-farnesylcysteine carboxyl methyltransferase enzymes. These enzymes recognize N-Acetyl-S-farnesyl-L-cysteine as a substrate through the farnesyl moiety, and occupation of the binding site blocks processing of farnesylated proteins by the enzyme. Carboxyl methylation of farnesylated proteins is an important modification that regulates protein function. Blockade of methyltransferase processing of platelet rap1 proteins by N-Acetyl-S-farnesyl-L-cysteine leads to inhibition of platelet aggregation. N-Acetyl-S-farnesyl-L-cysteine is also described to block the cellular movement and membrane adhesion of Ras proteins by interfering with carboxyl methylation processing. N-Acetyl-S-farnesyl-L-cysteine as a substrate for isoprenylated protein methyltransferase is described to block fMet-Leu-Phe-stimulated release of superoxide radical anion in neutrophil cells. Inhibition of neutrophil chemotaxis by N-Acetyl-S-farnesyl-L-cysteine also produces suppression of inflammatory response induced by 12-O-tereadecanoyl-phorbol-13-acetate and arachidonic acid.

应用:An inhibitor of S-farnesylcysteine methyl transferase

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs42022842   N-乙酰基-S-法呢基-L-半胱氨酸   25mg   2792.00   立即咨询
  abs42022842   N-乙酰基-S-法呢基-L-半胱氨酸   5mg   1166.00   立即咨询

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