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试剂描述:

产品名称:K 114

产品别名:(trans,trans)-1-Bromo-2,5-bis-(4-hydroxy)styrylbenzene; K114

CAS号:872201-12-2

英文别名:K 114

分子量:393.27

分子式:C₂₂H₁₇BrO₂

纯度:≥99%

外观:见爱必信官网

保存方法:Store at 4° C

描述:K 114 is a potent amyloid fibril-specific fluorescent dye similar to Congo Red and BSB . K 114 recognizes amyloid lesions and facilitates quantitative monitoring of the formation of amyloid fibrils assembled from the Aβ peptide, α-synuclein, and tau. The affinity for fibrils ranges 20-30 nM. Unlike the other compounds K114 has minimal fluorescence in aqueous buffers, but fluoresces brightly in the presence of amyloid fibrils. K114 can be used to monitor in vitro amyloid fibril formation by fluorescence emission at 550 nm.

应用:A potent amyloid fibril-specific fluorescent dye

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