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试剂描述:

产品名称:Australine, Hydrochloride, Castanospermum australe

产品别名:(1R,2R,3R,7S,7aR)-3-Hydroxymethyl-1,2,7-trihydroxypyrrolizidine HCI, 7.alpha.-Epialexine

CAS号:186766-07-4

英文别名:Australine, Hydrochloride, Castanospermum australe

分子量:225.67

分子式:C₈H₁₅NO₄?HCl

纯度:≥95%

外观:见爱必信官网

保存方法:Desiccate at -20° C

描述:Australine hydrochloride is a polyhydroxylated pyrrolizidine alkaloid that inhibits a-glucosidase, amyloglucosidase, and glucosidase I. Australine hydrochloride appears to be the first glucosidase inhibitor that is active toward glucosidase I but not glucosidase II. Inhibits glycoprotein processing at the gucosidase I step, resulting in the accumulation of glycoproteins containing Glc3Man7-9(GlcNAc)2-oligosaccharides. Does not inhibit a- or b-galactosidase, b-glucosidase, or a- or b-mannosidase.

应用:A pyrrolizidine inhibitor of glucosidase

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