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试剂描述:

产品名称:酪氨酸激酶

产品别名:

CAS号:81493-98-3

英文别名:酪氨酸激酶

分子量:1592.9

分子式:C₆₆H₁₀₉N₂₃O₂₃

纯度:>97%

外观:见爱必信官网

保存方法:Store at -20° C

描述:pp60v-src Autophosphorylation Site, Tyrosine Kinase Substrate Protein is a tyrosine kinase substrate with the ability to phosphorylate. Residues 2-12 in this peptide correspond to the sequence of the reported site of tyrosine phosphorylation (i.e. aa 412-422) in the Rous sarcoma virus (RSV)-encoded transforming protein pp60v-src. This substrate sequence, RRLIEDNEYTARG, was originally described as an EGFR (epidermal growth factor receptor) substrate in A431 cell extracts (K_m=0.3-0.6 mM). In vitro tyrosine phosphorylation of the peptide is stimulated by EGF (epidermal growth factor). The compound has shown an ability to reverse the kinase process much like DTT (1,4-Dithiothreitol) which has resulted in the increased activity of the insulin receptor/kinase.

应用:A tyrosine kinase substrate with ability to phosphorylate

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