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试剂描述:

产品名称:5-羟基癸酸钠

产品别名:

CAS号:624-00-0

英文别名:5-羟基癸酸钠

分子量:210.25

分子式:C₁₀H₁₉O₃?Na

纯度:≥98%

外观:见爱必信官网

保存方法:Store at -20° C

描述:5-Hydroxydecanoate Na (5-HD) is a substrate for mitochondrial outer membrane ACSL (acyl-CoA synthetase) that inhibits ATP-sensitive K⁺ channels. In neuronal type K sensitive ATP channel currents, 5-Hydroxydecanoate Na diminished the produced activation of the channels by PKG. On perfused rat hearts, 5-Hydroxydecanoate Na has shown the ability to inhibit the toxicity of 6-hyrdoxydopamine on dopaminergic neurons. 5-Hydroxydecanoate Na has displayed a lack of activity in inhibiting oxygen consuming mitochondria derived from skeletal muscle.

应用:An inhibitor of ATP-sensitive K⁺ channels

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