产地 | 上海 |
品牌 | 爱必信(absin) |
货号 | abs42020822 |
用途 | An unstable intermediate in the biosynthesis of LTB4 and LTC4 |
包装规格 | 50ug |
CAS编号 | 73466-12-3 |
纯度 | 0.97% |
是否进口 | 否 |
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试剂描述: 产品名称:(-)-白三烯 A4 甲基酯 产品别名: CAS号:73466-12-3 英文别名:(-)-白三烯 A4 甲基酯 分子量:332.5 分子式:C21H32O3 纯度:≥97% 外观:见爱必信官网 保存方法:Store at -80° C,1 year 描述:LTA4 (Leukotriene A4 methyl ester) is a member of the leukotriene family of endogenous metabolites of certain fatty acids and are related to thromboxanes and prostaglandins. They are potent eicosanoid lipid mediators that play numerous roles in inflammation, immunological functions and maintaining biological homeostasis. Leukotrienes possess a conjugated triene structure which gives them their name. They are generally isolated from leukocytes and primarily act through specific G protein-coupled receptors. Leukotriene A4 methyl ester is an unstable intermediate in the biosynthesis of LTB4 and LTC4 . Observations show that the naturally occuring free acid is a substrate for LTA4H (LTA4 hydrolase) and LTC4 synthase and plays a central role in transcellular leukotriene and lipoxin biosynthesis. It has also been shown to mobilize Ca2+ in human neutrophils. This product is supplied as the methyl ester for higher stability. 应用:An unstable intermediate in the biosynthesis of LTB4 and LTC4
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