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试剂描述:

产品名称:Palmitoyl Ethanolamide-d4

产品别名:Palmidrol-d4;PEA-7,7,8,8-d4

CAS号:1159908-45-8

英文别名:Palmitoyl Ethanolamide-d4

分子量:303.50

分子式:C₁₈H₃₃D₄NO₂

纯度:≥99% deuterated forms (d₁-d₄)

外观:见爱必信官网

保存方法:Store at -20° C,1 year.

描述:Palmitoyl Ethanolamide-d4 contains four deuterium atoms at the 7, 7', 8, and 8' positions and is intended for use as an internal standard for the quantification of PEA by GC- or LC-mass spectrometry. PEA is an endogenous cannabinoid found in brain, liver, and other mammalian tissues.1 PEA has also been isolated from egg yolk, and found to have anti-anaphylactic and anti-inflammatory activity in vitro.2 PEA is an endocannabinoid that has been shown to significantly elevate cyclic AMP in cells expressing peripheral cannabinoid (CB2) receptors, but its affinity for CB2 receptors is relatively low, at about 10 μM. Central cannabinoid (CB1) receptors have no appreciable affinity for PEA.3 Palmitoyl Ethanolamide-d4 is an activator of CB2, GPR55, PPAR α and CB1. Palmitoyl Ethanolamide-d4 is also a substrate of FAAH.

应用:A useful deuterium labeled palmitoyl ethanolamide

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