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试剂描述:

产品名称:双氢槲皮素

产品别名:黄杉素; 花旗松素; (2R,3R)-二氢槲皮素

CAS号:17654-26-1

英文别名:双氢槲皮素

分子量:304.25

分子式:C₁₅H₁₂O₇

纯度:≥90%

外观:见爱必信官网

保存方法:Store at 4° C

描述:(+)-Taxifolin is a flavanone compound which modulates chemopreventive genes through activation of the ARE. Studies show that (+)-Taxifolin up-regulates 65 genes including, NQO1, GSTM1, TXNRD1 and down-regulates 363 genes. In addition, (+)-Taxifolin can impede the influx of calcium required to up-regulate the expression of Mac-1-dependent neutrophil firm adhesion resulting in an anti-imflammatory effect. Alternately (+)-Taxifolin can inhibit ROS production by suppressing fMLP and PMA or by impairing the activation of NADPH . Furthermore, (+)-Taxifolin suppresses the secretion of apoB (apolipoprotein B) and increases the secretion of apoA-I (apolipoprotein A-I), which modulate hepatic lipid synthesis.

应用:A flavanon compound which modulates chemopreventive genes

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