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试剂描述:

产品名称:NFAT Activation Inhibitor III

产品别名:INCA-6

CAS号:3519-82-2

英文别名:NFAT Activation Inhibitor III

分子量:284.3

分子式:C₂₀H₁₂O₂

纯度:>95%

外观:见爱必信官网

保存方法:Store at room temperature

描述:NFAT Activation Inhibitor III (INCA-6) is a potent and selective inhibitor of calcineurin-NFAT (Nuclear Factor of Activated T cells) signaling. A quinone based compound that is cellularly permeable and blocks NFAT dephosphorylation. In experiments, this product particularly showed ability to prevent transient outward K⁺ current reduction in 3-Hz paced left ventricular cardiomyocytes following tachycardia. NFAT Activation Inhibitor III does not exhibit effects on calcineurin activity or on calcineurin’s downstream signaling.

应用:A potent and selective calcineurin-NFAT signaling inhibitor

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