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试剂描述:

产品名称:N-羟乙酰神经氨酸

产品别名:

CAS号:1113-83-3

英文别名:N-羟乙酰神经氨酸

分子量:325.3

分子式:C₁₁H₁₉NO₁₀

纯度:≥95%

外观:见爱必信官网

保存方法:Store at -20° C

描述:N-glycolylneuraminic acid (Neu5Gc) is a hydroxylated form of the generally known sialic acid N-acetylneuraminic acid, Neu5Ac . The compound is biosynthesized by the activity of cytidine monophosphate-N-acetylneuraminate (CMP-Neu5Ac) hydroxylase. Humans do not express Neu5Gc because there is an absence of the hydroxylase acitivity required to convert CMP-Neu5Ac to CMP-Neu5Ac. This is due to a mutation in the gene that occurred after the Homo-Pan divergence. Research shows that the parasite Trypanosoma cruzi contains N-glycoloylneuraminic acid, but is unable to synthesize sialic acids from their precursors.

应用:A hydroxylated form of sialic acid N-acetylneuraminic acid

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