产地 | 上海 |
品牌 | 爱必信(absin) |
货号 | abs42023784 |
用途 | A diazeniumdiolate NO donor |
包装规格 | 10mg |
CAS编号 | 146724-89-2 |
纯度 | 0.97% |
是否进口 | 否 |
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试剂描述: 产品名称:NOC-12 产品别名:1-羟基-2-氧代-3-(N-乙基-3-氨乙基)-3-乙基-1-三氮烯 CAS号:146724-89-2 英文别名:NOC-12 分子量:176.22 分子式:C6H16N4O2 纯度:≥97% 外观:见爱必信官网 保存方法:Store at -20° C 描述:NOC-12 is a diazeniumdiolate (NONOate) small molecule NO donor with a long NO release half-life of 327 minutes at 22°C. NOC-12 presents an NO donor with a half-life of release intermediate between NOC-9 (, half-life 2.7 min) and NOC-18 (, half-life 20 hr). NO release from NOC-12 and NOC-18 demonstrated inhibition of pulmonary artery smooth muscle cell proliferation with associated cGMP increase. NOC-12 mediated NO-release was shown to increase cGMP levels and protect cells against H2O2-induced damage and reperfusion. 应用:A diazeniumdiolate NO donor
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