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试剂描述:

产品名称:N-[(3R)-3-(二甲基氨基)-2,3,4,9-四氢-1H-咔唑-6-基]-4-氟苯甲酰胺盐酸盐

产品别名:

CAS号:186544-26-3

英文别名:N-[(3R)-3-(二甲基氨基)-2,3,4,9-四氢-1H-咔唑-6-基]-4-氟苯甲酰胺盐酸盐

分子量:387.88

分子式:C₂₁H₂₂N₃OF.HCl

纯度:>99%

外观:见爱必信官网

保存方法:Store at 4° C

描述:LY 344864 hydrochloride is a potent and selective SR-1F agonist with an EC₅₀ of 3 nM. This compound has been shown to display > 80-fold selectivity over other serotonin receptors (K_i values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 μM for SR-1F, SR-1A, SR-1B, SR-1D, SR-1E, SR-2B, SR-2C, SR-2A, and SR-7, respectively). Furthermore LY 344864 hydrochloride has been shown to inhibit neurogenic dural inflammation in vivo.

应用:A potent and selective SR-1F agonist

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