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试剂描述:

产品名称:2,3-双(2-羟基乙基硫代)-1,4-萘二酮

产品别名:

CAS号:93718-83-3

英文别名:2,3-双(2-羟基乙基硫代)-1,4-萘二酮

分子量:310.38

分子式:C₁₄H₁₄O₄S₂

纯度:>97%

外观:见爱必信官网

保存方法:Store at -20° C

描述:NSC 95397 is a selective and effective dual-specificity, quinone-based phosphatase inhibitor. The compound has been reported to inhibit Cdc25A, B and C, and is more selective than VH1-related dual-specificity phosphatase or protein tyrosine phosphatase 1b. Cdc25A is a phosphatase vital for the progression of the cell cycle and NSC 95397 has been noted to inhibit the G₂/M phase transition and cell growth. NSC 95397 has demonstrated the ability to activate ERK-1 and ERK-2, induce tyrosine phosphorylation of EGFR, activate caspase-3, and inhibit MKP-1 and MKP-3.

应用:A quinone-based Cdc25 inhibitor, caspase-3 activator, ERK activator, and MKP inhibitor

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