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产地 | 上海 |
品牌 | 爱必信(absin) |
货号 | abs42022257 |
用途 | An inhibitor of NOS3 |
包装规格 | 10mg |
CAS编号 | 150403-88-6 |
纯度 | 0.95% |
是否进口 | 否 |
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试剂描述: 产品名称:N5-(1-亚氨基乙基)-L-鸟氨酸盐酸盐(1:1) 产品别名: CAS号:150403-88-6 英文别名:N5-(1-亚氨基乙基)-L-鸟氨酸盐酸盐(1:1) 分子量:209.67 分子式:C7H15N3O2?HCl 纯度:≥95% 外观:见爱必信官网 保存方法:Store at -20° C 描述:N(5)-(1-Iminoethyl)-L-ornithine HCl (L-NIO), is an inhibitor of NOS3 (nitric oxide synthase) in the vascular endothelium that can halt endothelium-dependent relaxation induced by acteylcholine and cause endothelium-dependent contraction in aortic rings. Mechanistic studies have noted that L-NIO inhibits Ca2+-dependent NOS3 (eNOS). The same experiment on rat aorta has shown L-NIO to display a capacity to induce a dose-dependent increase in mean systemic arterial blood pressure. In addition, research has shown L-NIO to be the most potent inhibitor of the neutrophil and J774 enzymes compared to its analogues L-NMMA, L-NAME, and L-NNA. 应用:An inhibitor of NOS3
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