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试剂描述:

产品名称:2-[3-(4-戊基苯基)丙-2-烯酰氨基]苯甲酸

产品别名:

CAS号:110683-10-8

英文别名:2-[3-(4-戊基苯基)丙-2-烯酰氨基]苯甲酸

分子量:337.4

分子式:C₂₁H₂₃NO₃

纯度:≥99%

外观:见爱必信官网

保存方法:Store at room temperature

描述:N-(p-Amylcinnamoyl) anthranilic Acid (ACA), a cell permeable inhibitor of PLA₂, has been reported to inhibit α-ketoisocaproic acid and glyceraldehyde-induced insulin secretion, as well as glucose-induced insulin secretion. Additionally, by inhibiting PLA₂, ACA consequentially suppresses glucose-induced arachidonic acid formation in cells. Furthermore, research has shown ACA to modulate the activity of different transient receptor potential channels. In particular, ACA's blocking ability of diacylglycerol-activated TRP channels is of special interest since it offers the opportunity to interfere with receptor-induced Ca²⁺-dependent signaling processes in vascular smooth muscle cells and platelets.

应用:A TRP channel modulator and PLA2 inhibitor

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