公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)!

试剂描述:

产品名称:3-氧代-N-[(3S)-四氢-2-氧代-3-呋喃基]十二酰胺

产品别名:

CAS号:168982-69-2

英文别名:3-氧代-N-[(3S)-四氢-2-氧代-3-呋喃基]十二酰胺

分子量:297.39

分子式:C₁₆H₂₇NO₄

纯度:>98%

外观:见爱必信官网

保存方法:Store at -20° C

描述:N-3-oxo-dodecanoyl-L-homoserine lactone (3-oxo-C12-HSL) is one of the acylhomoserine lactone (AHL) molecules frequently identified in extracts of respiratory secretions from cystic fibrosis patients infected with P. aeruginosa and/or strains of the B. cepacia complex. It is involved in the activation of transcription factors NF-κB and AP-2, which in turn induce interleukin-8 production in human lung fibroblasts and epithelial cells, possibly contributing to the neutrophil infiltration and inflammation found in P. aeruginosa infections. N-3-oxo-dodecanoyl-L-Homoserine lactone may work to fight bacterial infection by quenching quorum sensing, a regulatory system used by bacterium to control gene expression in response to increasing cell density.

应用:An activator of transcription factors NF-κB and AP-2

产品信息订购:

产品更多信息请进入爱必信(absin)商城查看》》》

absin,您身边的科研百宝箱
专业提供试剂、耗材、仪器,在线订购,7*24h全国发货,方便快捷!