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试剂描述:

产品名称:N-去甲基西地那非

产品别名:

CAS号:139755-82-1

英文别名:N-去甲基西地那非

分子量:460.55

分子式:C₂₁H₂₈N₆O₄S

纯度:≥99%

外观:见爱必信官网

保存方法:Store at 4° C

描述:N-Desmethyl Sildenafil is a metabolite of Sildenafil . Sildenafil is a selective inhibitor of the type 5 cGMP phosphodiesterase (PDE5 inhibitor) which catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro-, synapto- and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. Sildenafil has also been shown to prevent indomethacin-induced small intestinal ulceration formation through an NO/cGMP- dependent mechanism.

应用:A potential selective type 5 phosphodiesterase inhibitor

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