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试剂描述:

产品名称:3-(苄基二甲基铵基)丙烷基磺酸

产品别名:

CAS号:81239-45-4

英文别名:3-(苄基二甲基铵基)丙烷基磺酸

分子量:257.4

分子式:C₁₂H₁₉NO₃S

纯度:>99%

外观:见爱必信官网

保存方法:Store at room temperature

描述:NDSB-256 is a nondetergent sulfobetaines class member. Unlike CHAPS and other zwittergents, NDSBs are nondenaturing even at 1 M concentrations. NDSBs have been used to improve the efficiency of solubilization of membrane proteins, to isolate nuclear proteins, to chromatographically purify halophilic proteins in low ionic strength buffers, and to crystallize proteins. They are zwitterionic over a wide pH range and do not absorb near UV range significantly. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. NDSBs can be easily removed by dialysis. At 1 M, NDSB-256 will restore 30% of the enzymatic activity of denatured egg white lysozyme; at 800 mM it will restore 16% of the enzymatic activity of denatured β-galactosidase.

应用:A nondetergent sulfobetaines class member

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