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产地 | 上海 |
品牌 | 爱必信(absin) |
货号 | abs42023505 |
用途 | A β-NAD analog. |
包装规格 | 5mg;25mg |
CAS编号 | 38806-38-1 |
纯度 | ≥95%% |
是否进口 | 否 |
产品描述 | |
描述 |
Nicotinamide 1,N6-ethenoadenine is an analog of β-NAD which can act as a fluorescent tag in nucleotide binary and ternary complex formation tests. The ADP-ribose moiety from NAD+ Free Acid and its analogs can be transferred to proteins and protein-bound ADP-ribose by PARP-1 (ADP Poly(ADP-ribosyl) transferase, pADPRT). These studies show that NAD+ is a better substrate in polymer synthesis reactions than Nicotinamide 1,N6-ethenoadenine. In addition, polyacrylamide gels show that proteins bound with ADP-ribose from Nicotinamide 1,N6-ethenoadenine show slower motility through the gel. This study suggests that Nicotinamide 1,N6-ethenoadenine is useful for studying enzymes degrading poly(ADP-ribose) as a result of this compounds fluorescent nature.
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应用 |
A β-NAD analog.
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纯度 |
≥95%
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储存/保存方法 |
Store at -20° C
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形态 |
Solid
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基本信息 | |
外观 |
Powder
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可溶性/溶解性 |
Soluble in water (250 mg/ml).
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MDL |
MFCD00063546
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PubChem CID |
170119
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