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产品展厅
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NNC 05-2090 hydrochloride；184845-43-0
- 品牌：爱必信(absin)
- 产地：上海
- 货号：abs42023725
- cas：184845-43-0
- 价格： ￥2716/瓶
- 发布日期： 2023-07-20
- 更新日期： 2024-09-09
产品详请
| 产地 | 上海 |
| 品牌 | 爱必信(absin) |
| 货号 | abs42023725 |
| 用途 | A GABA uptake inhibitor displaying selectivity for BGT-1 (mGAT-2) transporters |
| 包装规格 | 10mg;50mg |
| CAS编号 | 184845-43-0 |
| 纯度 | ≥99%% |
| 是否进口 | 否 |
| 产品描述 | |
| 描述 |
NNC 05-2090 hydrochloride is a GABA uptake inhibitor; displays moderate selectivity for BGT-1 (mGAT-2) transporters. GABA transporters belong to the solute carrier family 6 (SLC6) and are sodium- and chlorde-dependent members that mediate the rapid removal of GABA. NNC 05-2090 hydrochloride also displays affinity at α1- and D2-receptors (IC50 values are 266 and 1632 nM respectively). NNC 05-2090 hydrochloride is an inhibitor of GABA T-1, GABA T-2 and GABA T-3.
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| 应用 |
A GABA uptake inhibitor displaying selectivity for BGT-1 (mGAT-2) transporters
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| 纯度 |
≥99%
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| 储存/保存方法 |
Desiccate at room temperature
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| 形态 |
Solid
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| 基本信息 | |
| 沸点 |
643.1° C at 760 mmHg (Predicted)
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| 折射率 |
n20D ~1.62 (Predicted)
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| Ki 数据 |
BGT-1: Ki= 1.4 μM (human); GABA T-3: Ki= 15 μM (human); GABA T-1: Ki= 19 μM (human); GABA T-2: Ki= 41 μM (human)
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| 可溶性/溶解性 |
Soluble in DMSO (100 mM), and ethanol (13 mM).
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| MDL |
MFCD00952020
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| PubChem CID |
18782760
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