Norfloxacin nicotinate is a derivative of norfloxacin with improved solubility in water, and it acts as an antibacterial agent. This compound is reported to interfere with an ATP-induced structural transition of DNA complexed with DNA gyrase, and therefore inhibits the replication of bacterial DNA. Norfloxacin nicotinate has been shown to be effective against gram-negative bacteria, and effective, to a lesser degree, against gram-positive bacteria.

A fluoroquinolone antibacterial agent that is a norfloxacin derivative with improved solubility in water

98%，BR级

Store at -20° C

Solid

诺氟沙星烟酸盐

555.8° C at 760 mmHg (Predicted)

n20D 1.60 (Predicted)

DNA gyrase B: Ki= 0.09 nM (Escherichia coli); Topo IIβ: Ki= 1 ug ml-1 (human)

Soluble in water.

MFCD00873666

83908